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THYROID EYE DISEASE (TED) SIGNS AND SYMPTOMS IDENTIFICATION TOOL

Use this identification tool to recognize the signs and symptoms of TED in your patients

TED is a serious autoimmune disease with heterogenous presentation among patients.1 Early TED signs and symptoms may present like dry eye disease, allergies, or conjunctivitis.2-4 Use the tool below to explore TED signs and symptoms, see the impact TED can have on daily activities, and view questions to help initiate conversation with your patients.

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Create a personalized signs and symptoms sheet for your patient

Review and select the signs and symptoms your patient may be experiencing to create a personalized sheet. Use this sheet to navigate TED identification conversations with your patient.

The images provided above are for illustration purposes only. The severity of the signs or symptoms may differ for each patient. It is important to ask your patients if they have had or are currently experiencing any of these TED symptoms and how they may be impacting your patients’ emotional well-being, daily activities, and overall quality of life.

IGF-1R, insulin-like growth factor-1 receptor; MRI, magnetic resonance imaging; TSHR, thyroid-stimulating hormone receptor; T2, transverse relaxation time.

orbital-fibroblasts-and-inflammation-thyroid-eye-disease-pathophysiology

Learn about the cause of TED

See the changes occurring behind the eye before visual signs appear

checklist-icon

Create a personalized signs and symptoms sheet for your patient

Review and select the signs and symptoms your patient may be experiencing to create a personalized sheet. Use this sheet to navigate TED identification conversations with your patient.

  • REFERENCES

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    2. Couch SM. Thyroid Eye Disease: timely diagnosis is key to controlling this autoimmune condition. Glaucoma Today. January/February 2019. Accessed January 20, 2023. https://assets.bmctoday.net/glaucomatoday/pdfs/0119GT_F2_Couch.pdf
    3. Estcourt S, Hickey J, Perros P, Dayan C, Vaidya B. The patient experience of services for Thyroid Eye Disease in the United Kingdom: results of a nationwide survey. Eur J Endocrinol. 2009;161(3):483-487.
    4. Liaboe CA, Clark TJ, Simmons BA, Carter K, Shriver EM. Thyroid Eye Disease: an introductory tutorial and overview of disease. April 23, 2020. Accessed January 24, 2023. https://eyerounds.org/tutorials/thyroid-eye-disease/index.htm
    5. Barrio-Barrio J, Sabater AL, Bonet-Farriol E, Velázquez-Villoria Á, Galofré JC. Graves’ ophthalmopathy: VISA versus EUGOGO classification, assessment, and management. J Ophthalmol. 2015;2015:249125.
    6. Dolman PJ. Grading severity and activity in Thyroid Eye Disease. Ophthalmic Plast Reconstr Surg. 2018;34(4S suppl 1):S34-S40.
    7. Kahaly GJ, Petrak F, Hardt J, Pitz S, Egle UT. Psychosocial morbidity of Graves’ orbitopathy. Clin Endocrin (Oxf). 2005;63(4):395-402.
    8. Estcourt S, Vaidya B, Quinn A, Shepherd M. The impact of Thyroid Eye Disease upon patients’ wellbeing: a qualitative analysis. Clin Endocrinol (Oxf). 2008;68(4):635-639.
    9. Terwee C, Wakelkamp I, Tan S, Dekker F, Prummel MF, Wiersinga W. Long-term effects of Graves’ ophthalmopathy on health-related quality of life. Eur J Endocrinol. 2002;146(6):751-757.
    10. Bahn RS. Graves’ ophthalmopathy. N Engl J Med. 2010;362(8):726-738.
    11. Bartley GB, Fatourechi V, Kadrmas EF, et al. Long-term follow-up of Graves ophthalmopathy in an incidence cohort. Ophthalmol. 1996;103(6):958-962.
    12. Cockerham KP, Padnick-Silver L, Stuertz N, Francis-Sedlak M, Holt RJ. Quality of life in patients with chronic Thyroid Eye Disease in the United States. Ophthalmol Ther. 2021;10(4):975-987.
    13. Eyelid Dermatitis. Cleveland Clinic. Accessed April 26, 2024. https://my.clevelandclinic.org/health/diseases/21930-eyelid-dermatitis
    14. Bothun ED, Scheurer RA, Harrison AR, Lee MS. Update on Thyroid Eye Disease and management. Clin Ophthalmol. 2009;3:543-551.
    15. Chemosis. Mt Sinai. Accessed April 26, 2024. https://www.mountsinai.org/health-library/symptoms/chemosis#:~:text=Chemosis
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    17. Thyroid Eye Disease (TED) fact sheet. PreventBlindness.org. Accessed June 8, 2022. https://www.preventblindness.org/thyroid-eye-disease
    18. Verity DH, Rose GE. Acute Thyroid Eye Disease (TED): principles of medical and surgical management. Eye (Lond). 2013;27(3):308-319.
    19. American Thyroid Association. Graves’ eye disease brochure. Accessed September 1, 2022. https://www.thyroid.org
    20. McAlinden C. An overview of Thyroid Eye Disease. Eye Vis (Lond). 2014;1:9.